Post by Atticus Pizzaballa on Nov 25, 2021 20:03:11 GMT -5
Travel red list returns as fears grow over
UK health officials believe the new variant with 32 mutations, called B.1.1.529, may be the most dangerous yet to emerge
By
Joe Pinkstone,
SCIENCE CORRESPONDENT ;
Ben Riley-Smith,
POLITICAL EDITOR and
Charles Hymas,
South Africa is joining the red list from noon on Friday amid widespread concern over a new Covid-19 variant which has been detected in the country.
Neighbouring countries Botswana, Namibia, Zimbabwe, Eswatini and Lesotho will also be red-listed with flights temporarily banned.
The move marks a return to travel restrictions with anyone flying to the newly-red listed nations forced to spend 10 days in hotel quarantine on their return to the UK, with a £10,000 penalty for those flouting the rules.
🔎Read more: www.telegraph.co.uk/.../south-africa-red-listed.../
A new covid variant with an “extremely high” number of mutations and which could escape vaccines has been identified in three different countries, although case numbers are very small.
The B.1.1.529 strain, an offshoot of an old variant called B.1.1, has 32 spike mutations and has been found in South Africa, Botswana and one case in Hong Kong, where the person had recently travelled to South Africa.
So far only 10 cases of the variant have been spotted through genomic sequencing, but scientists say there could be more not yet identified. The profile of mutations is concerning due to its potential to dodge antibodies that can fight the virus.
New covid variants are identified by virologists all the time and often do not spread beyond a handful of cases. Even if they have the capacity to evade vaccines, if they are less transmissible than a dominant variant in a country they can quickly die out.
While the cluster is small, the case in Hong Kong exported from South Africa will fuel concerns that more infections will have spread through international travel.
Officials and scientists at the UK Health Security Agency (UKHSA) are monitoring and investigating the variant.
The Hong Kong case was a 36-year-old man who travelled to South Africa on 23 October and returned on 11 November. He tested negative on arrival back in Hong Kong but went on to test positive while at a quarantine hotel. The Hong Kong authorities have carried out compulsory testing at the apartment block where he lives.
In South Africa, the number of confirmed cases of covid has increased from 312 on Monday to more than 860 on Tuesday, although scientists believe it is too soon to tell whether there is a link with the new “super variant”.
The new variant was identified on Tuesday by Tom Peacock, a virologist at Imperial College London, who posted the details on a sequence-sharing forum and on Twitter.
The variant’s 32 spike mutations is described as “extremely high”. The Delta variant, now dominant across the world, has 16.
Spike mutations are essentially the virus’ “bag of tricks” that allow it to adapt and do different things such as become more transmissible, escape vaccines or become more deadly. It is not known whether B.1.1.529 is more transmissible or could beat Delta’s dominance.
Dr Peacock wrote: “Export to Asia implies this might be more widespread than sequences alone would imply. Also the extremely long branch length and incredibly high amount of spike mutations suggest this could be of real concern (predicted escape from most known monoclonal antibodies).”
Dr Peacock described the spike mutation profile as “really awful” and “horrific”.
He added: “Worth emphasising this is at super low numbers right now in a region of Africa that is fairly well sampled, however it very very much should be monitored due to that horrific spike profile (would take a guess that this would be worse antigenically than nearly anything else about).”
Variants that mutate to become more antigenic are more able to evade the antibodies that are built up through immunity from either vaccines or previous infection.
It is understood that all governments where the variant has been identified, in South Africa, Botswana and Hong Kong, are aware of the cases.
Dr Meera Chand, Covid-19 Incident Director at UKHSA, said: “The UK Health Security Agency, in partnership with scientific bodies across the globe, is constantly monitoring the status of SARS-CoV-2 variants as they emerge and develop worldwide.
“As it is in the nature of viruses to mutate often and at random, it is not unusual for small numbers of cases to arise featuring new sets of mutations. Any variants showing evidence of spread are rapidly assessed.”
inews.co.uk/news/politics/covid-super-variant-mutations-cases-found-south-africa-botswana-hong-kong-1316864
Here we go again. There is no end to this dangerous virus. It will be in the USA in a matter of week unless the lockdown over there works.
UK health officials believe the new variant with 32 mutations, called B.1.1.529, may be the most dangerous yet to emerge
By
Joe Pinkstone,
SCIENCE CORRESPONDENT ;
Ben Riley-Smith,
POLITICAL EDITOR and
Charles Hymas,
South Africa is joining the red list from noon on Friday amid widespread concern over a new Covid-19 variant which has been detected in the country.
Neighbouring countries Botswana, Namibia, Zimbabwe, Eswatini and Lesotho will also be red-listed with flights temporarily banned.
The move marks a return to travel restrictions with anyone flying to the newly-red listed nations forced to spend 10 days in hotel quarantine on their return to the UK, with a £10,000 penalty for those flouting the rules.
🔎Read more: www.telegraph.co.uk/.../south-africa-red-listed.../
A new covid variant with an “extremely high” number of mutations and which could escape vaccines has been identified in three different countries, although case numbers are very small.
The B.1.1.529 strain, an offshoot of an old variant called B.1.1, has 32 spike mutations and has been found in South Africa, Botswana and one case in Hong Kong, where the person had recently travelled to South Africa.
So far only 10 cases of the variant have been spotted through genomic sequencing, but scientists say there could be more not yet identified. The profile of mutations is concerning due to its potential to dodge antibodies that can fight the virus.
New covid variants are identified by virologists all the time and often do not spread beyond a handful of cases. Even if they have the capacity to evade vaccines, if they are less transmissible than a dominant variant in a country they can quickly die out.
While the cluster is small, the case in Hong Kong exported from South Africa will fuel concerns that more infections will have spread through international travel.
Officials and scientists at the UK Health Security Agency (UKHSA) are monitoring and investigating the variant.
The Hong Kong case was a 36-year-old man who travelled to South Africa on 23 October and returned on 11 November. He tested negative on arrival back in Hong Kong but went on to test positive while at a quarantine hotel. The Hong Kong authorities have carried out compulsory testing at the apartment block where he lives.
In South Africa, the number of confirmed cases of covid has increased from 312 on Monday to more than 860 on Tuesday, although scientists believe it is too soon to tell whether there is a link with the new “super variant”.
The new variant was identified on Tuesday by Tom Peacock, a virologist at Imperial College London, who posted the details on a sequence-sharing forum and on Twitter.
The variant’s 32 spike mutations is described as “extremely high”. The Delta variant, now dominant across the world, has 16.
Spike mutations are essentially the virus’ “bag of tricks” that allow it to adapt and do different things such as become more transmissible, escape vaccines or become more deadly. It is not known whether B.1.1.529 is more transmissible or could beat Delta’s dominance.
Dr Peacock wrote: “Export to Asia implies this might be more widespread than sequences alone would imply. Also the extremely long branch length and incredibly high amount of spike mutations suggest this could be of real concern (predicted escape from most known monoclonal antibodies).”
Dr Peacock described the spike mutation profile as “really awful” and “horrific”.
He added: “Worth emphasising this is at super low numbers right now in a region of Africa that is fairly well sampled, however it very very much should be monitored due to that horrific spike profile (would take a guess that this would be worse antigenically than nearly anything else about).”
Variants that mutate to become more antigenic are more able to evade the antibodies that are built up through immunity from either vaccines or previous infection.
It is understood that all governments where the variant has been identified, in South Africa, Botswana and Hong Kong, are aware of the cases.
Dr Meera Chand, Covid-19 Incident Director at UKHSA, said: “The UK Health Security Agency, in partnership with scientific bodies across the globe, is constantly monitoring the status of SARS-CoV-2 variants as they emerge and develop worldwide.
“As it is in the nature of viruses to mutate often and at random, it is not unusual for small numbers of cases to arise featuring new sets of mutations. Any variants showing evidence of spread are rapidly assessed.”
inews.co.uk/news/politics/covid-super-variant-mutations-cases-found-south-africa-botswana-hong-kong-1316864
Here we go again. There is no end to this dangerous virus. It will be in the USA in a matter of week unless the lockdown over there works.